| Following are the lakes whose name begins with "S" which are included in the 1999 LAKEWATCH Report. Click on the lake name to go to the page containing information on that lake. |
| Lake | County | Lake | County |
| Saddleback North | Hillsborough | South | Hillsborough |
| Saddleback South | Hillsborough | South Estella | Putnam |
| Saddlebags | Highlands | South Lake | Brevard |
| Sampson | Bradford | South Lotta | Orange |
| San Susan | Orange | SouthTalmadge | Volusia |
| Sanibel River | Lee | South Twin | Lake |
| Santa Fe | Alachua | Spencer | Lake |
| Santee | Palm Beach | Spirit | Polk |
| Santiago | Orange | Spivey | Citrus |
| Sarah | Orange | Spring | Clay |
| Saunders | Lake | Spring | Okaloosa |
| Sawyer | Orange | Spring | Orange |
| Sawyer | Volusia | Spring | Polk |
| Saxon North | Pasco | Spring | Seminole |
| Saxon South | Pasco | Spring | Walton |
| Sea Oats | Lee | Spring 2 | Orange |
| Searcy | Seminole | Spring Creek | Wakulla |
| Sebring | Highlands | Spring Garden | Volusia |
| Secret | Seminole | Spruce Creek | Volusia |
| Sellers | Lake | St. Andrew Bay | Bay |
| Seminary | Seminole | St. Kilda | Lee |
| Seminole | Jackson | St. Mark's River | Wakulla |
| Seminole | Pasco | Stall | Hillsborough |
| Shannon | Orange | Stanley | Orange |
| Sharon | St. Lucie | Stanley | Walton |
| Shaw | Volusia | Star | Putnam |
| Sheelar | Clay | Starke | Orange |
| Sheelin | Leon | Stella | Putnam |
| Sheen | Orange | Stemper | Hillsborough |
| Shelly Pond | Leon | Sterling | Broward |
| Shipp | Polk | Stillwataer | Hillsborough |
| Shoesole | Marion | Strawberry North | Hillsborough |
| Shortline 1-3 | Walton | Strawberry South | Hillsborough |
| Silver | Bradford | Sugarloaf A - L | Monroe |
| Silver | Hillsborough | Suggs | Putnam |
| Silver | Jackson | Summerset | Leon |
| Silver | Lake | Summit | Polk |
| Silver | Orange | Sunset | Hillsborough |
| Silver | Palm Beach | Sunset | Lake |
| Silver | Polk | Sunset Harbor | Marion |
| Silver | Putnam | Sunshine | Lake |
| Silver | Seminole | Susan | Lake |
| Silver Glen | Marion | Susan | Leon |
| Silver Paisley | Lake | Susannah | Orange |
| Simmons | Hillsborough | Suzy | DeSoto |
| Sirena | Highlands | Swan | Hillsborough |
| Smart | Polk | Swan | Putnam |
| Smith | Marion | Swatara | Lake |
| Smith | Orange | Sybelia | Orange |
| Snake | Hillsborough | Sylvan | Seminole |